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Dr. Miljan Simonovic
Associate Professor

  • B.S., Biochemistry, Summa Cum Laude, 1995
  • Faculty of Chemistry University of Belgrade, Belgrade, Serbia (Advisor: Prof. Vukić Šoškić)
  • Ph.D., Biochemistry, 2002 Department of Biochemistry University of Illinois at Chicago (Advisor: Prof. Peter G.W. Gettins)
  • Postdoctoral training, 2003-2008, Prof. Thomas A. Steitz Department of Molecular Biophysics and Biochemistry Yale University

Honors and Awards:
The Jane Coffin Childs Postdoctoral Fellowship, Yale University
The Dean's Scholarship, University of Illinois at Chicago
The University Fellowship, University of Illinois at Chicago
The Serbian Chemical Society Award
The Department of Biochemistry Award, University of Belgrade

Research Program:
More information on our research program can be found at:


Selected Publications

Holman KM, Wu J, Ling J, Simonović M (2015) The crystal structure of yeast mitochondrial ThrRS in complex with the canonical threonine tRNA, Nucleic Acids Res, pii: gkv1501.

French RL, Gupta N, Copeland PR, Simonović M (2014) Stoichiometry of the human terminal catalytic complex in selenocysteine synthesis, J Biol Chem 289, 28783-28794.

Ling J, Peterson KM, Simonović I, Cho C, Söll D, Simonović M (2012) Yeast mitochondrial threonyl-tRNA synthetase recognizes tRNA isoacceptors by distinct mechanisms and promotes CUN codon reassignment, Proc Natl Acad Sci USA 109, 3281-3286.

Palioura S, Sherrer RL, Steitz TA, Söll D, Simonović M (2009) Human SepSecS-tRNASec complex reveals the mechanism of selenocysteine formation, Science 325, 321-325.



Site: View Lab Website
Office: 312-996-0059
Lab: 312-996-0077


View Publications on PubMed